Please vote on
Voices to show your Support for Clean URL's for Profiles (yes, this uses Joomla standards)
How it Already Exists:
Awesome url's for profile's is already possible without the need of any SEF extension as
seen here (ignore the test subdomain). The structure is literally site.com/name (just like other major social media sites). To accomplish this I set the profile menu item as the homepage.
The problem and a Simple Solution:
The problem is that for guests there is no way to nicely show a frontpage considering that it's displaying a profile menu item to a non member. So what I'm proposing is a menu item option that allows the output to display nothing for guests (this will also speed up the frontpage). Here's what the admin option could look like:
By setting it to no, the frontpage does not load any content from ES (except modules that you might already be displaying). That is all we need from the stacked team, a way to display nothing for guests.

This allows you to create your own frontpage for guests by using modules and use Joomla's guest usergroup to assure that the menu item acts as both a profile portal and a frontpage. For the registered usergroup it's really easy to create an additional frontpage that uses site.com/home, the user will not know the difference.
Further Explaining:
So for a guest my frontpage could look like this:
http://www.alpineascent.com/
Once the user is logged in, the domain of the site will literally be their profile. The logo could link to site/home which will display the guest like frontpage.

If your concerned about menu items being over ran by these root urls, you can exclude username/permalink names in the custom field options.